Regeneration of Cation-Transport Capacity in HeLa Cell Membranes After Specific Blockade by Ouabain
The cardiac glycoside, ouabain, inhibits alkali-cation transport in HeLa cells. It binds to 0.75 × 10(6) sites per cell, and the half-time for its dissociation is 16 hr. After partial blockade by ouabain, the cell generates new ouabain-binding sites, with total restoration of transport in 10% of a c...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1972
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC427003/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4506784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.9.2627 |
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