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Lac Operator Analogues: Bromodeoxyuridine Substitution in the lac Operator Affects the Rate of Dissociation of the lac Repressor

As measured by a decreased rate of dissociation, lac repressor binds 10-times tighter to 5-bromodeoxyuridine-substituted lac operator than it does to normal lac operator. This result is obtained both in the absence and in the presence of isopropylthiogalactoside, an inducing ligand. These data are s...

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Detalhes bibliográficos
Main Authors: Lin, Syr-Yaung, Riggs, Arthur D.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC426991/
https://ncbi.nlm.nih.gov/pubmed/4560692
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