Cellular origin and regulation of D- and L-serine in in vitro and in vivo models of cerebral ischemia

D-Serine is known to be essential for the activation of the N-methyl-D-aspartate (NMDA) receptor in the excitation of glutamatergic neurons, which have critical roles in long-term potentiation and memory formation. D-Serine is also thought to be involved in NMDA receptor-mediated neurotoxicity. The...

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Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Abe, Takato, Suzuki, Masataka, Sasabe, Jumpei, Takahashi, Shinichi, Unekawa, Miyuki, Mashima, Kyoko, Iizumi, Takuya, Hamase, Kenji, Konno, Ryuichi, Aiso, Sadakazu, Suzuki, Norihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269747/
https://ncbi.nlm.nih.gov/pubmed/25294127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.164
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