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Differential Tiam1/Rac1 activation in hippocampal and cortical neurons mediates differential spine shrinkage in response to oxygen/glucose deprivation

Distinct neuronal populations show differential sensitivity to global ischemia, with hippocampal CA1 neurons showing greater vulnerability compared to cortical neurons. The mechanisms that underlie differential vulnerability are unclear, and we hypothesize that intrinsic differences in neuronal cell...

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Bibliografische gegevens
Gepubliceerd in:J Cereb Blood Flow Metab
Hoofdauteurs: Blanco-Suárez, Elena, Fiuza, Maria, Liu, Xun, Chakkarapani, Elavazhagan, Hanley, Jonathan G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269742/
https://ncbi.nlm.nih.gov/pubmed/25248834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.158
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