Differential Tiam1/Rac1 activation in hippocampal and cortical neurons mediates differential spine shrinkage in response to oxygen/glucose deprivation

Distinct neuronal populations show differential sensitivity to global ischemia, with hippocampal CA1 neurons showing greater vulnerability compared to cortical neurons. The mechanisms that underlie differential vulnerability are unclear, and we hypothesize that intrinsic differences in neuronal cell...

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Detalhes bibliográficos
Publicado no:J Cereb Blood Flow Metab
Main Authors: Blanco-Suárez, Elena, Fiuza, Maria, Liu, Xun, Chakkarapani, Elavazhagan, Hanley, Jonathan G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269742/
https://ncbi.nlm.nih.gov/pubmed/25248834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.158
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