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H(2)CO(3) as Substrate for Carbonic Anhydrase in the Dehydration of HCO(3)(-)

Carbonic anhydrase, a metalloenzyme containing one zinc atom per protein molecule of molecular weight 30,000, catalyzes the interconversion of CO(2) and HCO(3)(-) in solution. The rate of catalysis, among the fastest known, is pH-dependent, with a pK(Enz) near neutral. Arguments are presented to sho...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Koenig, Seymour H., Brown, Rodney D.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1972
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4627028/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.9.2422
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