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Severe deficiency of coagulation Factor VII results in spontaneous cardiac fibrosis in mice
Mice genetically modified to produce low levels (~1% of wild-type) of coagulation FVII presented with echocardiographic evidence of heart abnormalities. Decreases in ventricular size and reductions in systolic and diastolic functions were found, suggestive of a restrictive cardiomyopathy, and consis...
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| Publicado no: | J Pathol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269473/ https://ncbi.nlm.nih.gov/pubmed/18973189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2454 |
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