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THE AP-2 CLATHRIN ADAPTOR MEDIATES ENDOCYTOSIS OF AN INHIBITORY KILLER CELL Ig-LIKE RECEPTOR (KIR) IN HUMAN NK CELLS()

Stable surface expression of human inhibitory killer cell immunoglobulin-like receptors (KIR) is critical for controlling NK cell function and maintaining NK cell tolerance toward normal MHC-I(+) cells. Our recent experiments, however, have found that antibody-bound KIR3DL1 (3DL1) readily leaves the...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Purdy, Amanda K., Alvarez-Arias, Diana A., Oshinsky, Jennifer, James, Ashley M., Serebriiskii, Ilya, Campbell, Kerry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269369/
https://ncbi.nlm.nih.gov/pubmed/25238755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303406
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