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Biochemical and Cellular Specificity of Peptide Inhibitors of G Protein-Coupled Receptor Kinases

Identifying novel allosteric inhibitors of G protein-coupled receptor kinases (GRKs) would be of considerable use in limiting both the extent of desensitization of GPCRs as well as downstream positive regulation through GRKs. Several peptides have previously been identified as inhibitors of specific...

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Udgivet i:Int J Pept Res Ther
Main Authors: Baameur, Faiza, Hammitt, Richard A., Friedman, Jacqueline, McMurray, John S., Clark, Richard B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269301/
https://ncbi.nlm.nih.gov/pubmed/25530741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10989-013-9357-9
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