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Hemoglobin Switching in Sheep and Goats: Change in Functional Globin Messenger RNA in Reticulocytes and Bone Marrow Cells
Anemia causes a change in the type of circulating hemoglobin in goats and certain sheep: HbA (α(2)β(2)(A)) is replaced by HbC (α(2)β(2)(C)). We have isolated globin mRNA from erythroid cells of anemic and nonanemic animals to investigate the mechanism whereby anemia causes this switch. To study seve...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1972
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426896/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4506088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.8.2184 |
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