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Loss of Simian Virus 40 DNA-RNA Hybrids from Nitrocellulose Membranes; Implications for the Study of Virus-Host DNA Interactions

Complete hybrids of simian virus 40 (SV40)DNA and its complementary RNA (cRNA) are not retained on nitrocellulose membranes. At saturating cRNA concentrations, retention of the hybrids indicates incomplete homology between DNA and RNA, probably due to incorporation of host DNA in the viral DNA; this...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Haas, Martin, Vogt, Marguerite, Dulbecco, Renato
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1972
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4340749/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.8.2160
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