Acetylcholinesterase of the sand fly, Phlebotomus papatasi (Scopoli): construction, expression and biochemical properties of the G119S orthologous mutant

BACKGROUND: Phlebotomus papatasi vectors zoonotic cutaneous leishmaniasis. Previous expression of recombinant P. papatasi acetylcholinesterase (PpAChE1) revealed 85% amino acid sequence identity to mosquito AChE and identified synthetic carbamates that effectively inhibited PpAChE1 with improved spe...

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Détails bibliographiques
Publié dans:Parasit Vectors
Auteurs principaux: Temeyer, Kevin B, Tong, Fan, Totrov, Maxim M, Tuckow, Alexander P, Chen, Qiao-hong, Carlier, Paul R, Pérez de León, Adalberto A, Bloomquist, Jeffrey R
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268798/
https://ncbi.nlm.nih.gov/pubmed/25491113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-014-0577-4
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