Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

Transformation of E. coli cells treated with CaCl(2) to multiple antibiotic resistance by purified R-factor DNA is reported. Drug resistance is expressed in a small fraction of the recipient bacterial population almost immediately after uptake of DNA, but full genetic expression of resistance requir...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Cohen, Stanley N., Chang, Annie C. Y., Hsu, Leslie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1972
Schlagworte:	Biological Sciences: Microbiology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4559594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.8.2110
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