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The dosage of Patz1 modulates reprogramming process

The acquisition of pluripotent cells can be achieved by combined overexpression of transcription factors Oct4, Klf4, Sox2 and c-Myc in somatic cells. This cellular reprogramming process overcomes various barriers to re-activate pluripotency genes and re-acquire the highly dynamic pluripotent chromat...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Hui, Ow, Jin Rong, Tan, Bobby Cheng Peow, Goh, Ziyi, Feng, Bo, Loh, Yuin Han, Fedele, Monica, Li, Hu, Wu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268633/
https://ncbi.nlm.nih.gov/pubmed/25515777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07519
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