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The dosage of Patz1 modulates reprogramming process
The acquisition of pluripotent cells can be achieved by combined overexpression of transcription factors Oct4, Klf4, Sox2 and c-Myc in somatic cells. This cellular reprogramming process overcomes various barriers to re-activate pluripotency genes and re-acquire the highly dynamic pluripotent chromat...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268633/ https://ncbi.nlm.nih.gov/pubmed/25515777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07519 |
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