Single-Dose Pharmacokinetics of Methylphenidate Extended-Release Multiple Layer Beads Administered as Intact Capsule or Sprinkles Versus Methylphenidate Immediate-Release Tablets (Ritalin(®)) in Healthy Adult Volunteers

Objectives: The purpose of this study was to evaluate the relative bioavailability and safety of a multilayer extended-release bead methylphenidate (MPH) hydrochloride 80 mg (MPH-MLR) capsule or sprinkles (37% immediate-release [IR]) versus MPH hydrochloride IR(Ritalin(®)) tablets, and to develop a...

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Publicado en:J Child Adolesc Psychopharmacol
Main Authors: Adjei, Akwete, Teuscher, Nathan S., Kupper, Robert J., Chang, Wei-Wei, Greenhill, Laurence, Newcorn, Jeffrey H., Connor, Daniel F., Wigal, Sharon
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2014
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268571/
https://ncbi.nlm.nih.gov/pubmed/25514542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cap.2013.0135
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