Human Papillomavirus Type 16 E7 Oncoprotein Causes a Delay in Repair of DNA Damage

BACKGROUND AND PURPOSE: Patients with Human papillomavirus related (HPV+) head and neck cancers (HNCs) demonstrate improved clinical outcomes compared to traditional HPV negative (HPV−) HNC patients. We have recently shown that HPV+ HNC cells are more sensitive to radiation than HPV− HNC cells. Howe...

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Pubblicato in:Radiother Oncol
Autori principali: Park, Jung Wook, Nickel, Kwangok P., Torres, Alexandra D., Lee, Denis, Lambert, Paul F., Kimple, Randall J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268372/
https://ncbi.nlm.nih.gov/pubmed/25216575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2014.08.026
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