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Dosing in neonates: Special considerations in physiology and trial design
Determining the right dose for drugs used to treat neonates is critically important. Neonates have significant differences in physiology affecting drug absorption, distribution, metabolism, and elimination that makes extrapolating dosages from adults and older children inappropriate. In spite of rec...
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| Publicado no: | Pediatr Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268272/ https://ncbi.nlm.nih.gov/pubmed/25268145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.143 |
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