Role of DNA and Specific Cytoplasmic Receptors in Glucocorticoid Action

Glucocorticoids induce tyrosine aminotransferase (EC 2.6.1.5) synthesis in cultured rat hepatoma cells. These steroids penetrate the cell membrane and bind to specific cytoplasmic receptor proteins. The resulting complex binds to the nucleus. This nuclear binding has now been studied in a cell-free...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Baxter, John D., Rousseau, Guy G., Benson, M. Christina, Garcea, Robert L., Ito, James, Tomkins, Gordon M.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1972
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4403081/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.7.1892
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