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Correlation Between Decreased CSF α-Synuclein and Aβ(1-42) in Parkinson Disease

Accumulation of misfolded α-synuclein (α-syn) protein in Lewy bodies and neurites is the cardinal pathologic feature of Parkinson disease (PD), but abnormal deposition of other proteins may also play a role. Cerebrospinal fluid (CSF) levels of proteins known to accumulate in PD may provide insight i...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Buddhala, Chandana, Campbell, Meghan C., Perlmutter, Joel S., Kotzbauer, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268043/
https://ncbi.nlm.nih.gov/pubmed/25212463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.07.043
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