Characterization of the Mutagenic Spectrum of 4-Nitroquinoline 1-Oxide (4-NQO) in Aspergillus nidulans by Whole Genome Sequencing

4-Nitroquinoline 1-oxide (4-NQO) is a highly carcinogenic chemical that induces mutations in bacteria, fungi, and animals through the formation of bulky purine adducts. 4-NQO has been used as a mutagen for genetic screens and in both the study of DNA damage and DNA repair. In the model eukaryote Asp...

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Foilsithe in:G3 (Bethesda)
Main Authors: Downes, Damien J., Chonofsky, Mark, Tan, Kaeling, Pfannenstiel, Brandon T., Reck-Peterson, Samara L., Todd, Richard B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2014
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Investigations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267943/
https://ncbi.nlm.nih.gov/pubmed/25352541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.014712
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