Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

Through epithelial-mesenchymal transition (EMT), cancer cells acquire enhanced ability of migration and invasion, stem cell like characteristics and therapeutic resistance. Notch signaling regulates cell-cell connection, cell polarity and motility during organ development. Recent studies demonstrate...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Yuan, Xun, Wu, Hua, Han, Na, Xu, Hanxiao, Chu, Qian, Yu, Shiying, Chen, Yuan, Wu, Kongming
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267749/
https://ncbi.nlm.nih.gov/pubmed/25477004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0087-z
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