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Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application
Through epithelial-mesenchymal transition (EMT), cancer cells acquire enhanced ability of migration and invasion, stem cell like characteristics and therapeutic resistance. Notch signaling regulates cell-cell connection, cell polarity and motility during organ development. Recent studies demonstrate...
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| Pubblicato in: | J Hematol Oncol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267749/ https://ncbi.nlm.nih.gov/pubmed/25477004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0087-z |
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