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Arsenite-Induced Pseudo-Hypoxia Results in Loss of Anchorage-Dependent Growth in BEAS-2B Pulmonary Epithelial Cells

Epidemiology studies have established a strong link between lung cancer and arsenic exposure. Currently, the role of disturbed cellular energy metabolism in carcinogenesis is a focus of scientific interest. Hypoxia inducible factor-1 alpha (HIF-1A) is a key regulator of energy metabolism, and it has...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zhao, Fei, Malm, Scott W., Hinchman, Alyssa N., Li, Hui, Beeks, Connor G., Klimecki, Walter T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267735/
https://ncbi.nlm.nih.gov/pubmed/25513814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114549
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