Shoc2/Sur8 Protein Regulates Neurite Outgrowth

The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained ERK phosphorylation, notably in the case of EGF s...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Leon, Gonzalo, Sanchez-Ruiloba, Lucia, Perez-Rodriguez, Andrea, Gragera, Teresa, Martinez, Natalia, Hernandez, Silvia, Anta, Berta, Calero, Olga, Garcia-Dominguez, Carlota A., Dura, Lara M., Peña-Jimenez, Daniel, Castro, Judit, Zarich, Natasha, Sanchez-Gomez, Pilar, Calero, Miguel, Iglesias, Teresa, Oliva, Jose L., Rojas, Jose M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267731/
https://ncbi.nlm.nih.gov/pubmed/25514808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114837
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