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Shoc2/Sur8 Protein Regulates Neurite Outgrowth

The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained ERK phosphorylation, notably in the case of EGF s...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leon, Gonzalo, Sanchez-Ruiloba, Lucia, Perez-Rodriguez, Andrea, Gragera, Teresa, Martinez, Natalia, Hernandez, Silvia, Anta, Berta, Calero, Olga, Garcia-Dominguez, Carlota A., Dura, Lara M., Peña-Jimenez, Daniel, Castro, Judit, Zarich, Natasha, Sanchez-Gomez, Pilar, Calero, Miguel, Iglesias, Teresa, Oliva, Jose L., Rojas, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267731/
https://ncbi.nlm.nih.gov/pubmed/25514808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114837
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