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Locating the uracil-5-yl radical formed upon photoirradiation of 5-bromouracil-substituted DNA
In a previous study, we found that 2-deoxyribonolactone is effectively generated in the specific 5-bromouracil ((Br)U)-substituted sequence 5′-(G/C)[A](n) (= 1,2)(Br)U(Br)U-3′ and proposed that a formed uracil-5-yl radical mainly abstracts the C1′ hydrogen from the 5′-side of (Br)U(Br)U under 302-nm...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267621/ https://ncbi.nlm.nih.gov/pubmed/25398904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1133 |
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