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Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation

Wnt signaling is a critical regulator of bone development, but the identity and role of the Wnt-producing cells are still unclear. We addressed these questions through in situ hybridization, lineage tracing, and genetic experiments. First, we surveyed the expression of all 19 Wnt genes and Wnt targe...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tan, Si Hui, Senarath-Yapa, Kshemendra, Chung, Michael T., Longaker, Michael T., Wu, Joy Y., Nusse, Roeland
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267375/
https://ncbi.nlm.nih.gov/pubmed/25422448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1420463111
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