Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest

Loss of Pax3, a developmentally regulated transcription factor expressed in pre-migratory neural crest, results in severe developmental defects and embryonic lethality. Although Pax3 mutations produce profound phenotypes, the intrinsic transcriptional activation exhibited by Pax3 is surprisingly mod...

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Publicat a:Cell Rep
Autors principals: Manderfield, Lauren J., Engleka, Kurt A., Aghajanian, Haig, Gupta, Mudit, Yang, Steven, Li, Li, Baggs, Julie E., Hogenesch, John B., Olson, Eric N., Epstein, Jonathan A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267159/
https://ncbi.nlm.nih.gov/pubmed/25466249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.10.061
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