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Hydroxylation index of omeprazole in relation to CYP2C19 polymorphism and sex in a healthy Iranian population
BACKGROUND: Polymorphism of CYP2C19 gene is one of the important factors in pharmacokinetics of CYP2C19 substrates. Omeprazole is a proton pump inhibitor which is mainly metabolized by cytochrome P450 2C19 (CYP2C19). The aim of present study was to assess omeprazole hydroxylation index as a measure...
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| Publicado no: | Daru |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4266903/ https://ncbi.nlm.nih.gov/pubmed/25498969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40199-014-0081-6 |
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