Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-c...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Parasitol Drugs Drug Resist
Hauptverfasser: Simoes-Pires, Claudia, Hostettmann, Kurt, Haouala, Amina, Cuendet, Muriel, Falquet, Jacques, Graz, Bertrand, Christen, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2014
Schlagworte:
Invited Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266807/
https://ncbi.nlm.nih.gov/pubmed/25516845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2014.07.001
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