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Hepatic stellate cells secretes type I collagen to trigger epithelial mesenchymal transition of hepatoma cells

Liver fibrosis is a risk factor for hepatoma. Activated hepatic stellate cells (HSCs) play a critical role in progression of hepatoma. Resected hepatoma patients with high α-SMA+HSCs infiltration had worse survival, OR: 2.2 and p=0.0434. We hypothesized that HSCs could increase the epithelial-mesenc...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Yang, Ming-Chen, Wang, Chih-Jung, Liao, Pao-Chi, Yen, Chia-Jui, Shan, Yan-Shen
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266709/
https://ncbi.nlm.nih.gov/pubmed/25520865
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