Neuroinvasion of the Highly Pathogenic Influenza Virus H7N1 Is Caused by Disruption of the Blood Brain Barrier in an Avian Model

Influenza A virus (IAV) causes central nervous system (CNS) lesions in avian and mammalian species, including humans. However, the mechanism used by IAV to invade the brain has not been determined. In the current work, we used chickens infected with a highly pathogenic avian influenza (HPAI) virus a...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chaves, Aida J., Vergara-Alert, Júlia, Busquets, Núria, Valle, Rosa, Rivas, Raquel, Ramis, Antonio, Darji, Ayub, Majó, Natàlia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266681/
https://ncbi.nlm.nih.gov/pubmed/25506836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115138
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