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Negative Selection of Self-Reactive Chicken B Cells Requires B Cell Receptor Signaling and Is Independent of the Bursal Microenvironment
Although the negative selection of self-reactive B cells in the bone marrow of mammals has been clearly demonstrated, it remains unclear in models of gut-associated B cell lymphopoiesis, such as that of the chicken (Gallus gallus). We have generated chicken surface IgM–related receptors in which the...
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| Publié dans: | J Immunol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4266589/ https://ncbi.nlm.nih.gov/pubmed/24516196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302394 |
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