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Functional and Genomic Context in Pathway Analysis of GWAS Data

Gene set analysis (GSA) is a promising tool for uncovering the polygenic effects associated with complex diseases. However, the available techniques reflect a wide variety of hypotheses about how genetic effects interact to contribute to disease susceptibility. The lack of consensus about the best w...

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Detalhes bibliográficos
Publicado no:Trends Genet
Main Authors: Mooney, Michael A., Nigg, Joel T., McWeeney, Shannon K., Wilmot, Beth
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266582/
https://ncbi.nlm.nih.gov/pubmed/25154796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2014.07.004
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