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Structural study of a small molecule receptor bound to dimethyllysine in lysozyme

Lysine is a ubiquitous residue on protein surfaces. Post translational modifications of lysine, including methylation to the mono-, di- or trimethylated amine result in chemical and structural alterations that have major consequences for protein interactions and signalling pathways. Small molecules...

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Veröffentlicht in:Chem Sci
Hauptverfasser: McGovern, Róise E., Snarr, Brendan D., Lyons, Joseph A., McFarlane, James, Whiting, Amanda L., Paci, Irina, Hof, Fraser, Crowley, Peter B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266562/
https://ncbi.nlm.nih.gov/pubmed/25530835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02383h
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