Promoter Decommissioning by the NuRD Chromatin Remodeling Complex Triggers Synaptic Connectivity in the Mammalian Brain

Precise control of gene expression plays fundamental roles in brain development, but the roles of chromatin regulators in neuronal connectivity have remained poorly understood. We report that depletion of the NuRD complex by in vivo RNAi and conditional knockout of the core NuRD subunit Chd4 profoun...

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Publicado no:Neuron
Main Authors: Yamada, Tomoko, Yang, Yue, Hemberg, Martin, Yoshida, Toshimi, Cho, Ha Young, Murphy, J. Patrick, Fioravante, Diasynou, Regehr, Wade G., Gygi, Steven P., Georgopoulos, Katia, Bonni, Azad
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266462/
https://ncbi.nlm.nih.gov/pubmed/24991957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.05.039
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