In Vitro and in Vivo Evaluation of Water-Soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer

[Image: see text] A series of organometallic ruthenium(II) complexes containing iminophosphorane ligands have been synthesized and characterized. Cationic compounds with chloride as counterion are soluble in water (70–100 mg/mL). Most compounds (especially highly water-soluble 2) are more cytotoxic...

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Pubblicato in:J Med Chem
Autori principali: Frik, Malgorzata, Martínez, Alberto, Elie, Benelita T., Gonzalo, Oscar, Ramírez de Mingo, Daniel, Sanaú, Mercedes, Sánchez-Delgado, Roberto, Sadhukha, Tanmoy, Prabha, Swayam, Ramos, Joe W., Marzo, Isabel, Contel, María
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266334/
https://ncbi.nlm.nih.gov/pubmed/25409416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5012337
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