Bone morphogenetic protein 4 (BMP4) promotes mammalian oogonial stem cell differentiation via Smad1/5/8 signaling

OBJECTIVE: To test whether bone morphogenetic protein 4 (BMP4) directly regulates differentiation of adult mouse ovary-derived oogonial stem cells (OSCs) in vitro. DESIGN: Animal study. SETTING: Research laboratory. ANIMAL(S): Adult C57BL/6 female mice. INTERVENTION(S): After purification from adult...

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Udgivet i:Fertil Steril
Main Authors: Park, Eun-Sil, Woods, Dori C., Tilly, Jonathan L.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266321/
https://ncbi.nlm.nih.gov/pubmed/23993924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2013.07.1978
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