Detection of DNA Synthesis in Intact Organisms with Positron-Emitting [Methyl-(11)C]Thymidine
(11)CO(2) produced in the Brookhaven 152-cm cyclotron was converted to formaldehyde, which in turn was used for the enzymatic conversion of deoxyuridine-5′-phosphate to [(11)C]thymidylate. Enzymatic treatment of the nucleotide with alkaline phosphatase gave [(11)C]thymidine. The preparation of [(11)...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1972
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4554538/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.4.988 |
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