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Inhibition of Collagen Secretion from Bone and Cultured Fibroblasts by Microtubular Disruptive Drugs

Collagen synthesis in chick-embryo frontal bone and 3T3 fibroblasts from mice was measured by incorporation in vitro of [(14)C]proline into collagenase-digestible material. About 15-25% of the collagen synthesized by the frontal bone in 60 min, and 60% of that synthesized by the fibroblasts in 2 hr,...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Diegelmann, Robert F., Peterkofsky, Beverly
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1972
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426589/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4502941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.4.892
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