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Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol

Recent studies reported a broad but selective antiviral activity of 25-hydroxycholesterol (25HC) against enveloped viruses, being apparently inactive against non-enveloped viruses. Here we show that 25HC is endowed with a marked antiviral activity against three pathogenic non-enveloped viruses, i.e....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Civra, Andrea, Cagno, Valeria, Donalisio, Manuela, Biasi, Fiorella, Leonarduzzi, Gabriella, Poli, Giuseppe, Lembo, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265783/
https://ncbi.nlm.nih.gov/pubmed/25501851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07487
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