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Covalent Attachment of a Peptidyl-Transfer RNA Analog to the 50S Subunit of Escherichia coli Ribosomes

The peptidyl-tRNA analog, N-bromo-acetyl-Phenylalanyl-tRNA(Phe) has been prepared. Its binding to the 70S ribosome of E. coli is totally dependent upon polyuridylic acid. The analog becomes covalently attached to the 50S particle. It is associated with only one protein fraction after polyacrylamide-...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pellegrini, Maria, Oen, Helen, Cantor, Charles R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1972
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4554533/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.4.837
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