Proteasome dysfunction induces muscle growth defects and protein aggregation

The ubiquitin–proteasome and autophagy–lysosome pathways are the two major routes of protein and organelle clearance. The role of the proteasome pathway in mammalian muscle has not been examined in vivo. In this study, we report that the muscle-specific deletion of a crucial proteasomal gene, Rpt3 (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Cell Sci
Päätekijät: Kitajima, Yasuo, Tashiro, Yoshitaka, Suzuki, Naoki, Warita, Hitoshi, Kato, Masaaki, Tateyama, Maki, Ando, Risa, Izumi, Rumiko, Yamazaki, Maya, Abe, Manabu, Sakimura, Kenji, Ito, Hidefumi, Urushitani, Makoto, Nagatomi, Ryoichi, Takahashi, Ryosuke, Aoki, Masashi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2014
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265737/
https://ncbi.nlm.nih.gov/pubmed/25380823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.150961
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