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Proteasome dysfunction induces muscle growth defects and protein aggregation
The ubiquitin–proteasome and autophagy–lysosome pathways are the two major routes of protein and organelle clearance. The role of the proteasome pathway in mammalian muscle has not been examined in vivo. In this study, we report that the muscle-specific deletion of a crucial proteasomal gene, Rpt3 (...
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| 出版年: | J Cell Sci |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265737/ https://ncbi.nlm.nih.gov/pubmed/25380823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.150961 |
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