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Podosome-regulating kinesin KIF1C translocates to the cell periphery in a CLASP-dependent manner

The kinesin KIF1C is known to regulate podosomes, actin-rich adhesion structures that remodel the extracellular matrix during physiological processes. Here, we show that KIF1C is a player in the podosome-inducing signaling cascade. Upon induction of podosome formation by protein kinase C (PKC), KIF1...

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Publicat a:J Cell Sci
Autors principals: Efimova, Nadia, Grimaldi, Ashley, Bachmann, Alice, Frye, Keyada, Zhu, Xiaodong, Feoktistov, Alexander, Straube, Anne, Kaverina, Irina
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265736/
https://ncbi.nlm.nih.gov/pubmed/25344256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.149633
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