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Proof of dual-topology architecture of Fluc F(-) channels with monobody blockers

Fluc-type F(-) channels — used by microorganisms for resisting fluoride toxicity — are unusual in their quaternary architecture: They are thought to associate as dimers with the two subunits in antiparallel transmembrane orientation. Here we subject this unusual structural feature to a direct test....

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Stockbridge, Randy B., Koide, Akiko, Miller, Christopher, Koide, Shohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265568/
https://ncbi.nlm.nih.gov/pubmed/25290819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6120
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