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New Method to Prepare N-t-Butoxycarbonyl Derivatives and the Corresponding Sulfur Analogs from di-t-Butyl Dicarbonate or di-t-Butyl Dithiol Dicarbonates and Amino Acids

Di-t-butyl dicarbonate and one of its dithiol analogs, practical methods of preparation for which are given, react with amino-acid esters to form the N-t-butoxycarbonyl (t-BOC) derivatives and the thiol analogs in good yield under mild conditions. The thiol analogs are stable to acidic conditions, w...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Tarbell, D. Stanley, Yamamoto, Yutaka, Pope, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1972
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16591972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.3.730
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