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De novo prediction of cis-regulatory elements and modules through integrative analysis of a large number of ChIP datasets

BACKGROUND: In eukaryotes, transcriptional regulation is usually mediated by interactions of multiple transcription factors (TFs) with their respective specific cis-regulatory elements (CREs) in the so-called cis-regulatory modules (CRMs) in DNA. Although the knowledge of CREs and CRMs in a genome i...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Niu, Meng, Tabari, Ehsan S, Su, Zhengchang
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265420/
https://ncbi.nlm.nih.gov/pubmed/25442502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1047
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