Epithelial–stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues

Intrinsic Notch signaling in intestinal epithelial cells restricts secretory cell differentiation. In gut-associated lymphoid tissue (GALT), stromal cells located beneath the follicle-associated epithelium (FAE) abundantly express the Notch ligand delta-like 1 (Dll1). Here, we show that mice lacking...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Obata, Yuuki, Kimura, Shunsuke, Nakato, Gaku, Iizuka, Keito, Miyagawa, Yurika, Nakamura, Yutaka, Furusawa, Yukihiro, Sugiyama, Machiko, Suzuki, Keiichiro, Ebisawa, Masashi, Fujimura, Yumiko, Yoshida, Hisahiro, Iwanaga, Toshihiko, Hase, Koji, Ohno, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264932/
https://ncbi.nlm.nih.gov/pubmed/25378482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201438942
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