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The proteasome activity reporter GFP-Cl1 is degraded by autophagy in the aging model Podospora anserina

The degradation of damaged proteins is an important vital function especially during aging and stress. The ubiquitin proteasome system is one of the major cellular machineries for protein degradation. Health and longevity are associated with high proteasome activity. To demonstrate such a role in ag...

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Bibliografske podrobnosti
izdano v:F1000Res
Main Authors: Wiemer, Matthias, Osiewacz, Heinz D.
Format: Artigo
Jezik:Inglês
Izdano: F1000Research 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264638/
https://ncbi.nlm.nih.gov/pubmed/25520781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.5337.1
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