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The proteasome activity reporter GFP-Cl1 is degraded by autophagy in the aging model Podospora anserina

The degradation of damaged proteins is an important vital function especially during aging and stress. The ubiquitin proteasome system is one of the major cellular machineries for protein degradation. Health and longevity are associated with high proteasome activity. To demonstrate such a role in ag...

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Bibliografiske detaljer
Udgivet i:F1000Res
Main Authors: Wiemer, Matthias, Osiewacz, Heinz D.
Format: Artigo
Sprog:Inglês
Udgivet: F1000Research 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264638/
https://ncbi.nlm.nih.gov/pubmed/25520781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.5337.1
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