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Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity

Neural progenitor cells (NPCs) derived from human pluripotent stem cells (hPSCs) are a multipotent cell population that is capable of nearly indefinite expansion and subsequent differentiation into the various neuronal and supporting cell types that comprise the CNS. However, current protocols for d...

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Publicat a:Stem Cell Reports
Autors principals: Moya, Noel, Cutts, Josh, Gaasterland, Terry, Willert, Karl, Brafman, David A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264562/
https://ncbi.nlm.nih.gov/pubmed/25458891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.004
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