Potential role of the lectin pathway of complement in the pathogenesis and disease manifestations of systemic sclerosis: a case-control and cohort study

INTRODUCTION: Repetitive episodes of ischemia and reperfusion (I/R) are a cardinal feature of the pathogenesis of systemic sclerosis (SSc), which precedes tissue fibrosis. The complement system is a key mediator of tissue damage after I/R, primarily by activation of the lectin pathway. This study in...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Osthoff, Michael, Ngian, Gene-Siew, Dean, Melinda M, Nikpour, Mandana, Stevens, Wendy, Proudman, Susanna, Eisen, Damon P, Sahhar, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264552/
https://ncbi.nlm.nih.gov/pubmed/25403109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0480-6
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